Genomic Instability and DNA Repair (B4) 2011

The maintenance of genomic integrity following DNA damage depends on the coordination of DNA repair, cell cycle progression, transcriptional and post-transcriptional regulation and apoptosis. The integrity of the DNA damage response pathways plays a critical role in human health. This meeting will present the most recent advance in the field and reveal how a complex network of signaling transduction pathways are involved in DNA damage response. The topics include early detection of DNA lesions, DNA damage checkpoint control, DNA repair, genotoxic damage in cancer stem cells, modulation of DNA damage signaling by microRNAs, systems biology approaches to DNA damage and the use of cutting edge technologies in the study of DNA damage responses.