HIV Evolution, Genomics and Pathogenesis (X7) 2011

Elucidating the molecular mechanisms of HIV pathogenesis relies on understanding the complex interplay between the virus and its host. Increasingly, the field is relying on the power of comparative studies of similar viruses in other species, and on whole genome analyses to elucidate which pathways are critical. The use of evolutionary analyses of both host and virus is also providing novel insights into viral transmission and innate immune responses. This Keystone Symposia meeting will use diverse disciplines to promote further insights into the dynamic interplay between the virus and the host in areas of pathogenesis, mucosal biology, the roles of viral and host genes, and viral latency. Understanding these issues is critical for the design and development of an effective vaccine and the next generation of antiviral agents.