Biocatalysis as a Tool for the Synthetic Chemist 2018 is a conference that covers topics such as:
- Hydrolytic enzymes (lipases, esterases, amidases, proteases)
- Kinetic resolution
- Mechanism of hydrolysis by enzymes
- Dynamic kinetic resolution (DKR)
- Use of organic solvents
- Ester, amide, nitrile and epoxide hydrolysis
- Deracemisation
- Concentration
- Introduction to biocatalysis
- Myths about biocatalysis / pros and cons of biocatalysis
- Literature sources for biocatalysis (books and review articles)
- Sources of biocatalysts
- Enzyme / protein basics, basic microbiology
- Enzyme types
- Equipment requirements
- Reduction
- Co-factors
- Ketone reduction, Prelog rules
- Enantioselective reduction / DKR
- Deracemisation of secondary alcohols
- C=C reduction
- Keto-ester reduction
- Oxidations
- Amine oxidation, deracemisation of amines and amino acids
- Alcohol oxidation
- Demethylation
- Bio-oxygenation, bio-hydroxylation
- Bayer-Villiger oxidation
- Epoxidation
- Sulphoxidation
- Scale up of biotransformations
- C-c and c-x bond formation
- Transketolases
- Aldol reactions
- Hydroxy-nitrile lyases
- Cross benzoin reactions
- Transamination
- Michael reactions
- Fumarase and aspartase
- Pros and cons of biocatalysis
- New developments including directed evolution
- Mutagenesis
- Polymerase Chain Reaction
- Product isolation
- Directed Evolution
Biocatalysis as a Tool for the Synthetic Chemist 2018 brings together Organic Chemists involved in:
- Designing novel
- Synthesis
- Green synthetic routes
