Clinically Relevant Drug Transporters 2013

Clinically Relevant Drug Transporters 2013 is a conference that covers topics such as:

• Deriving pre-clinical kinetic parameters for the prediction of clinically-relevant DDIs for in vitro-in vivo extrapolation studies
• Case studies on emerging ITC transporters of clinical importance including MATEs, MRP2, BSEP and PEPT1
• Bench-to-bedside consequences of genetic polymorphisms for novel transporters and their implications for stratified medicine
• Applying modelling and simulation techniques to determine the interaction of clinically-relevant co-medicines
• Strategic approaches to ensure regulatory approval during pre-clinical research for transport proteins in the kidney, liver, intestine and brain
• OATPB1 variability and clinical outcome studies
• Mathematically modelling structure-function activity relationships to rationally target transporters of interest
• Harmonising different cell-based screening systems to ensure inter-assay validity