Bioinformatics & Drug Discovery Technology 2015

Bioinformatics & Drug Discovery Technology 2015 is a seminar dedicated to the latest science and technology used in bioinformatics and drug discovery & designing. the course will be of great help to students/ researchers/ scientists in learning this latest science and technology.

Key Topics

• Homology Modeling – Modeller and Swiss Modeling
• Sequence Alignment - Pairwise Sequence Alignment – Blast, Multiple Sequence Alignment – Clustalw, ClustalX, Clustal Omega
• Protein-Protein Interaction Analysis – String and Mint databases
• Protein Domain Analysis – Interproscan
• Introduction of Drug Discovery & Designing
• Basic Linux commands and Perl and Bioperl programming
• Virtual screening
• Science involved in disease target identification
• Conversion of Mol files to Pdb files by Open Babel
• In-silico generation of ligands by ChemSketch
• Molecular Docking by MGL Tools
• Protein optimization & Energy Minimization by SPDV
• Running the Docking Algorithm by Cygwin
• Creation of Grid Parameter & Dock Parameter files by AutoDock Software
• Look for H-bond Between ligand and active site of the residue of protein by UCSF Chimera
• Selection of potent inhibitors on the basis of binding energies and Lipinski`s Rule of 5
• Prediction of Bioactivity
• Prediction of Molecular Properties
• Bioavailability & ADME
• Drug Likeness
• Toxicity

Who should Attend

Researchers, students and scientists.