5th Annual Oligonucleotide Analytical Development & CMC and Summit

The 5th Annual Oligonucleotide Analytical Development & CMC and Summit explores scalable oligonucleotide analytical development and CMC strategies through advanced synthesis, process control, impurity profiling, stereochemical consistency, and regulatory readiness for next-generation oligonucleotide therapeutics.

Key topics

• Scalable oligonucleotide manufacturing and process control strategies
• Analytical development for raw material characterization and upstream control
• Stereochemical consistency in siRNA, ASO, and conjugated oligonucleotides
• Impurity profiling and quality control for oligonucleotide therapeutics
• Commercial manufacturing validation and analytical method transfer
• Enzymatic ligation and alternative oligonucleotide synthesis technologies
• Digital quality control and sequencing-driven impurity intelligence
• CMC readiness and technology transfer for IND and commercial programs
• Analytical toolkits for structurally complex oligonucleotide modalities
• Regulatory compliance and lifecycle management for oligonucleotide products
• Scale-up strategies for GMP oligonucleotide production
• Process variability reduction and manufacturing comparability

Who should attend

• Oligonucleotide analytical development scientists
• CMC and GMP manufacturing professionals
• Pharmaceutical and biotechnology researchers
• Process development and scale-up specialists
• Regulatory affairs and quality assurance professionals
• Analytical chemistry and impurity profiling experts
• Scientists working on siRNA, ASO, and gRNA therapeutics
• Technology transfer and commercial manufacturing teams
• Bioprocess and oligonucleotide synthesis engineers
• Professionals involved in oligonucleotide therapeutics development