3rd Annual Protein Degradation for CNS Summit

3rd Annual Protein Degradation for CNS Summit is a conference dedicated to Delivering and Translating Degraders of Extracellular and Intracellular CNS Proteins.

Key Topics

• Proteasome & beyond: detailing strategies for degrading intracellular & extracellular cns proteins
• Demonstrating state-of-the-art cns degraders to supercharge development
• Optimizing protein degrader physicochemical properties to improve delivery across the blood brain barrier
• Mapping locations & understanding mechanisms of action for brain-specific e3 ligases
• Overcoming the barriers to translaton to unlock clinical success in cns protein degradation
• Discovering target proteins & maximizing screening strategies to ensure protein degrader specificity to cns indications