2nd Annual Vaccine Manufacturing Conference 2010

During the period 2008-2013, the most important development in influenza vaccines, will be the diversification of influenza manufacturing. New cell-based technologies will be used, and eventually replace, existing egg-based manufacturing methods. Many cell-culture vaccines are being developed under grants from the US government.

Key themes:
An overview of cell culture technology: The latest developments on cell-culture based vaccine production
Cell line selection and development
Mammalian cell culture processes for large scale operation
Glycan analysis in cell culture-based influenza vaccine production
Influence of host cell line and virus strain on the glycosylation pattern of viral Haemagglutinin
Bulk Production, microcarrier cultures and free-cell suspension cultures
Downstream processing parameters for purification, filling, and packaging of the cell culture based vaccines
Flow cytometric monitoring of influenza virus infection
Validation of cell culture based processes & qualification of associated equipment and facility
Analysing ventures of global vaccines manufacturers in the developing world
Regulatory issues associated with the development of cell-based influenza vaccine