Autophagy is an important catabolic process that contributes to cell survival, cell growth and cell differentiation, in model cell systems and in whole organisms. It is implicated in a number of human diseases including cancer, bowel disease and neurodegeneration, and has also been shown to play important roles in infectious disease.
Autophagy is a degradative pathway which requires the formation of a special double membrane vesicle (the autophagosome) to sequester and deliver components to the lysosome. Over recent years our understanding of the basic mechanisms of the process including the signalling pathways involved and the mechanisms of autophagosome biogenesis, maturation and trafficking has evolved rapidly. Furthermore, the recent data implicating autophagy in human diseases has catalysed and developed widespread, cross-disciplinary interest. This Harden Conference will focus on basic mechanisms and disease processes, and will highlight the most recent advances in the field.
Topics - Atg proteins
- Autophagy
- Cell death
- mTOR
- nutrient sensing
- PI3P binding proteins
The conferences bring together scientists from various backgrounds with a common interest in - but varying approaches to - the topic of the conference.
To maintain a suitably high level of discussion and presentation at the conference, it is desirable that participants be experienced in the field covered; most of the participants will be expected to have postdoctoral or equivalent experience, although Ph.D. students will also be welcome.
The planned scientific sessions feature speakers invited by the Organizers and, in addition, time is left for extensive discussion and for short contributions, including posters, by other conference participants.
All participants must be resident for the duration of the conference. Scientists wishing to participate are asked to apply online.
