LNP Characterization and Analytical Development Summit

  • 12-14 Sep 2023
  • Hilton Boston Back Bay, MA, United States

Description

The LNP Characterization and Analytical Development Summit covers topics such as:

  • Fundamentals of LNP Structure to Relay into Analytical
  • Experimental & Quantitative Analytical Platforms to Inform the Translational Gap from Bench to Bed
  • Advanced Methods to Characterize LNP Heterogeneity and Encapsaultion
  • Overcoming Heterogeneity of LNP Structure & Morphology to Establish a Greater Understanding of Encapsulation Efficiency
  • Morphology of the LNP to Advance Understanding of the Functional Impact
  • Translating the Structural Properties of the LNP to Develop Methods to Overcome Heterogeneity Challenges
  • Linking LNP Physicochemical and Biological Properties to Better Understand their Safety
  • Aligning the Industry approach of Quality Control Metrics to Translate Data Efficiently to Maximize Integrity & Purity of the LNP Complex
  • Analysing the Lipid Composition Following LNP Formulation to Increase Nanoparticle Purification
  • Optimizing Payload Characterization to Better Predict LNP Complex Outcome
  • Quality of the Payload Prior to LNP Encapsulation
  • Strategies of Characterizing Co-formulated LNPs to Ensure Precision of Analytics
  • Structure and Conformation of mRNA-Lipid Nanoparticles
  • Potency Assay Development to Establish the Required Breadth of Assays Capable of Presenting Total Functionality
  • Breadth of Potency Assays Available to Industry to Initiate a Matrix Approach
  • Appropriate Reference Material to Establish Batch to Batch Consistency
  • Advancements in Technology to Improve Efficiency of Analytical Methods
  • Technology Available to Execute Thorough Characterization of LNPs
  • Endosomal Release & Cellular Uptake to Quantify the Efficiency of Payload Delivery
  • Assay Development to Comprehensively Measure Endosomal Release
  • The Future of LNP – What is Next for Characterization & Analytical Development Research?

Past Events

Important

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Event Categories

Health & Medicine: Medical technology, Pharma

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